Technegas is an ultra-fine dispersion of Technetium-labelled carbon, produced by heating Technetium-99m in a carbon crucible for a few seconds at 2,750 degrees Celsius. The resultant gas-like Technegas, thus produced in a Technegas generator, is a cluster of nano-sized (~35nm) pure carbon platelets of hexagonal shape fully encapsulating Technetium metal crystals. The small size and hydrophobic properties together confirm ideal characteristics for gas-like behaviour on inhalation into the lungs.
Once inhaled by the patient suspected of having a Pulmonary Embolism, the patient is then imaged under a gamma camera in the ventilation part of a Ventilation/Perfusion SPECT scan. Technegas penetrates to the sub-segmental areas of the lung and is trapped by surfactant in the alveolar walls.
The Technegas generator is a mobile, microprocessor which produces Technegas in a safe and controlled environment. With the uptake in SPECT imaging, V/Q SPECT results with Technegas can be argued to be superior to Planar imaging and CT when comparing Specificity, Sensitivity, Accuracy and Negative Predictive Value.
Of significant interest, when compared to CT, is the low radiation dose imparted by V/Q SPECT imaging. This is important in all patients but particularly in young women with proliferating breast tissue.
No other diagnostic imaging method has proven itself more effective than the V/Q scan in the diagnosis of Pulmonary Embolism. Technegas, used in the ventilation part of the V/Q scan, is cost-effective, simple to perform and accurate. Study after study confirm that spiral CT should not be used in isolation to exclude a diagnosis of PE and negative findings on CT cannot definitely exclude PE.
“Lung Scintigraphy has a superior sensitivity combined with adequate specificity and low rate of non-diagnostic tests. The low radiation dose, the possibility to quantify the degree of embolism and to use the test for follow-up of treatment of embolism and its feasibility in very sick patients, contribute to the priority of lung scintigraphy over Computed Tomographic Pulmonary Angiography. Bajc et al, 2002”.
Add up the benefits using Technegas
- Proven diagnostic accuracy: Sensitivity, specificity and accuracy at least equivalent of CTPA giving the clinician interpretative confidence first time every time.
- Non-invasive: Aids patients comfort and compliance.
- Detects PE: Even at subsegmental levels.
- Low radiation burden to the patient: In compliance with ALARA principles and FDA recommendation, Technegas is the right exam, for the right reason, at the right time.
- A true ‘screening’ test: A true screening test should have universal application and minimal exclusion criteria. Technegas may be administered to almost all patients including those who are
– Renally compromised
– Diabetics on Metformin
– Critically ill
– Suffered from M.I.
– Allergic to iodinated contrast
– On long term anticoagulants
– Female under 45
Why Technegas for ventilation imaging
|For the Clinician||For the Technologist|
|Quick reliable administration of Technegas, available around the clock.
-Rapid results at your convenience.
|Quick and simple automated procedure.
-Frees up your preparation time.
|Gas like behaviour of Technegas coupled with the ideal energy of Tc-99m.
-Excellent penetration to peripheral areas.
|Rapid and easy administration (2-3 breaths suffice for most patients).
-Rapid results, kinder to your patient.
-Improved patient compliance.
|Images may be acquired in multiple projections.
-Improved identification of mismatching defects.
|Reduced radiation exposure to operator and to patient.
|Long residence time and absence of redistribution enables acquisition of high quality SPECT images.
-Reduces reported indeterminate scans to less than 5%.
|Minimal camera time required.
-Enhances your camera time management.
|“Technegas Lung SPECT Studies…can improve sensitivity 96% and specificity 97%. We conclude that V/P imaging can be improved significantly by V/P SPECT using Technegas – Lemb et al 2001”
-Technegas can enhance the service you offer your clinical colleagues and your patients.
|Flexible solution to your needs.
-Easy to fit in with departmental scheduling.
|Provides a simple answer to a single question.
-Allows accurate and quick decisions.
|Exceptional image quality.
-Facilitates image interpretation.
|Minimal radiation burden for the patient.
-May reduce radiation induced sequellae.
Ultralute is a revolutionary innovation that allows Nuclear Medicine departments to increase the productivity of their Tc-99m generator. It does this by allowing you to elute any amount of activity in approximately 1.5ml. By increasing the concentration of Tc-99m from an elution, the decay profile and the growth of Tc-99m from a Mo-99m/Tc 99m generator can be better utilised.